ESAT-6 peptide recognition by bovine CD8+ lymphocytes of naturally infected cows in herds from southern Italy.

نویسندگان

  • Fabrizio Vitale
  • Stefano Reale
  • Enrico Petrotta
  • Santo Caracappa
  • Annalisa Barera
  • Marco Pio La Manna
  • Pasquale Macaluso
  • Nadia Caccamo
  • Francesco Dieli
  • Hans Martin Vordermeier
  • Guido Sireci
  • Alfredo Salerno
چکیده

The aim of this study was to define epitopes of Mycobacterium bovis from ESAT-6 (early secretory antigen of 6 kDa) recognized by CD8+ T lymphocytes from cows naturally infected with Mycobacterium bovis. We found that bovine CD8+ T cells recognized 10 out of 11 ESAT-6 peptides tested.

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عنوان ژورنال:
  • Clinical and vaccine immunology : CVI

دوره 13 4  شماره 

صفحات  -

تاریخ انتشار 2006